• Users Online: 530
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2013  |  Volume : 25  |  Issue : 1  |  Page : 37-41

The effect of chronic khat chewing on liver enzyme levels ( a Yemenian study)


1 Department of Tropical Medicine and Liver, Cairo University, Cairo, Egypt
2 Department of Hepato-gastroenterology, Sana'a University, Sana'a, Yemen

Correspondence Address:
Mohammad Abdelbary
MD, Department of Tropical Medicine and Liver, Cairo University, Cairo
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.7123/01.EJIM.0000425957.34390.61

Rights and Permissions

Background

Khat is a natural stimulant from the Catha edulis plant, which grows mainly in Yemen. The liver has been suspected to be vulnerable to the harmful effects of khat use.

Aim

The aim of the study was to investigate the effect of khat chewing on the liver function in healthy Yemeni individuals.

Methods

Liver function tests were performed on 30 chronic khat chewers (group I) and 20 individuals who did not chew khat (group II).

Results

Twenty percent of group I and only 5% of group II reported abnormally elevated alanine transaminase (ALT) levels, with no statistically significant difference between the mean ALT values (P=0.208); 13.3% of group I showed elevated aspartate aminotransferase levels (P=0.058). With regard to other liver function tests there was no statistically significant difference between the two groups. ALT levels increased with increasing duration of khat chewing.

Conclusion

Chronic khat chewing causes subclinical hepatocellular damage, whereas transient khat chewing has no effect on the liver function.



[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2662    
    Printed22    
    Emailed0    
    PDF Downloaded291    
    Comments [Add]    

Recommend this journal