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CASE REPORT
Year : 2017  |  Volume : 29  |  Issue : 2  |  Page : 83-85

BCR/ABL positive thrombocythemia: a diagnostic dilemma


1 Department of Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India
2 Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India

Correspondence Address:
Lubna Zafar
4/1074, Sir Syed Nagar, Near Nadeem Tarin Hall, Aligarh - 202 002, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejim.ejim_21_16

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Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients. We report here a case of a 45-year-old men who presented with thrombocytosis. Bone marrow aspiration yielded small megakaryocytes with hypolobulated nuclei and positive BCR-ABL rearrangement. A diagnosis of BCR-ABL+ essential thrombocythemia was made and imatinib was advised.


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