The Egyptian Journal of Internal Medicine

REVIEW ARTICLE
Year
: 2019  |  Volume : 31  |  Issue : 4  |  Page : 397--402

A review of bone marrow niche cellular spectrum


Sabry A Shoieb1, Mohammad A Abdel Hafez1, Alaa E Abd El-Hamid1, Walaa Hamdy Ezz2 
1 Department of Internal Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt
2 Department of Nephrology, Zifta General Hospital, Gharbeya, Egypt

Correspondence Address:
MBBCh Walaa Hamdy Ezz
El Monshat El Kubra, Markaz El Santa, Elgharbia, 31758
Egypt

To perform a narrative review on the role of bone marrow (BM) niche in normal hematopoiesis. MEDLINE databases and Ovid database were searched. The search was performed on 10 October 2018 and included articles published from 2015 to 2018 in English language. The initial search presented 45 articles, which were included in the study. Hematopoietic stem cells which produce a variety of hematopoietic lineage cells throughout the life are located in a specialized microenvironment called the ‘niche’ in the BM where they are governed. Several types of cells in the BM have been suggested to contribute to hematopoietic stem cell niche activity.


How to cite this article:
Shoieb SA, Abdel Hafez MA, Abd El-Hamid AE, Ezz WH. A review of bone marrow niche cellular spectrum.Egypt J Intern Med 2019;31:397-402


How to cite this URL:
Shoieb SA, Abdel Hafez MA, Abd El-Hamid AE, Ezz WH. A review of bone marrow niche cellular spectrum. Egypt J Intern Med [serial online] 2019 [cited 2020 Sep 22 ];31:397-402
Available from: http://www.esim.eg.net/article.asp?issn=1110-7782;year=2019;volume=31;issue=4;spage=397;epage=402;aulast=Shoieb;type=0